JetBall TFT
The air-cushioned spherical treadmill allows a restrained rodent to navigate in virtual space presented on a 270° TFT surround monitor.
Behavioural Systems
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Mightex Systems, with operations based in Toronto, Canada, and in the Silicon Valley,
California, is a leading supplier of photonic products and services for a broad spectrum of
applications including industrial imaging, bio-photonic solutions, LED illumination, machine
vision, life & health sciences, and industrial test & measurement etc.
Website:
https://www.mightexbio.com/
Mightex OASIS Implant – Freely Behaving Cellular Resolution Calcium Imaging and Optogenetics
Understand the Link Between Neural Circuits and Behaviour
The OASIS Implant is a ground-breaking platform for simultaneous cellular-resolution optogenetics and calcium imaging in freely-behaving animals to probe complex neuronal networks in the deep-brain, cortex, and multiple brain regions, or spinal cord.
- Freely-Behaving Calcium Imaging and Optogenetics
- Cellular-Resolution Optogenetics
- Multi-Region Investigation
- Reconfigurable Platform
- High-Quality Imaging with Scientific Cameras
A Different Approach to Integrated Freely-Behaving Calcium Imaging and Optogenetics
To offer neuroscientists the ability to stimulate and visualize individual neurons in freely-behaving animals, Mightex’s engineers went back to the drawing board and pioneered a new path in the in vivo calcium imaging field. Instead of miniaturizing and placing the microscope on the animal – thereby limiting the microscope’s features and the animal’s behaviour – we kept the microscope out of the animal’s head by making use of long and flexible imaging fibers.
How It Works
By keeping the microscope away from the animal’s head, the OASIS Implant accomplishes 2 main goals:
Whitepaper
Mightex OASIS Macro – Cortex-Wide Imaging and Optogenetics System
Mesoscope for Optical Imaging and Targeted Optogenetics
The OASIS Macro is a mesoscopic platform for all-optical targeted optogenetics and calcium imaging. The OASIS Macro enables researchers to simultaneously image the entire mouse cortex and perform targeted optogenetics (with Mightex’s market-leading Polygon pattern illuminator).
- Large field of view for in vivo imaging and optogenetics
- Targeted optogenetics
- Reconfigurable platform
- Designed for in vivo experiments
Reconfigurable In Vivo Mesoscopic Platform for Imaging and Optogenetics
Mightex’s OASIS Macro is designed as a reconfigurable optical mesoscope system for in vivo imaging and optogenetics. The final system can be tailored to performance requirements for unique applications. This can include major features such as adding a second and third illumination source, or a dual-camera imaging system, as well as fine details including compatibility features for certain cameras and objectives.
Mightex OASIS Micro – In Vivo Cellular-Resolution Optogenetics and Imaging System
Microscope Imaging and Cellular-Resolution Optogenetics Platform
The OASIS Micro is a ground-breaking microscope platform for all-optical cellular-resolution optogenetics and imaging in small cortical or deep-brain areas of a head-fixed animal. Simultaneously image small cortical or deep brain regions and perform neuron-specific targeted optogenetics with the addition of Mightex’s Polygon pattern illuminator.
- Small cortical area or deep-brain for in vivo imaging and optogenetics
- Cellular-resolution optogenetics
- Reconfigurable platform
- Designed for in vivo experiments
Reconfigurable In Vivo Microscope Platform for Imaging and Optogenetics
Mightex’s OASIS Micro is designed as a reconfigurable optical microscope system for in vivo imaging and optogenetics. The final system can be tailored to performance requirements for unique applications. This can include major features such as adding a second and third illumination source, or a dual-camera imaging system, as well as fine details including compatibility features for certain cameras and objectives.
PhenoSys is a research- and development-oriented company based in Berlin, Germany. They engineer
and market cutting edge technology for automated animal behaviour research. Their team draws on
extensive expertise of electrical and mechanical engineering, computer science, and behavioural
biology.
PhenoSys offers unique, automated instrumentation in the field of behaviour biology. This
includes specialised applications of virtual reality and touch screen technology for animal
behaviour environments and RFID (transponder) operated devices in home cage environments.
Phenosys’ experimental systems are used for behavioural phenotyping, brain research,
experimental psychology, and the diagnostic characterisation of animal models for translational
medicine.
Website:
https://www.phenosys.com/
Virtual Reality for uncovering neural dynamics in decision making.
Virtual Reality Systems enable rats and mice to enter a virtual reality world. These platforms
offer a revolutionary concept for research on animal learning, memory, cognition, and
navigation. They provide an environment of optimal control when investigating how animals
process complex information. Furthermore, simple and complex behaviour can be explored
in-depth.
Their VR platforms are highly flexible and modular solutions. Stimulation is not only visual but
can be extended to 3D sound, odours and tactile information. It is easy to interface to existing
hard- and software for in-vivo measurements or brain stimulation.
JetBall Dome
The JetBall Dome allows a rodent to navigate in a virtual world presented by projecting into a spherical 1.2m igloo type screen.
DoubleDisk Treadmill
The Double Disk is a state-of-the-art virtual reality system that uniquely combines the exploratory freedom of a spherical treadmill with the running stability of a linear treadmill, designed for dynamic and flexible animal behavior research.
Moculus - True 3D VR Immersion
Moculus is a turnkey head-fixed behavior system that delivers unparalleled 3D Virtual Reality, enabling natural, unbiased behavioral experiments with high-resolution insights.
SpeedBelt
The PhenoSys SpeedBelt is a linear treadmill designed for stand-alone applications or for the integration with their JetBall VR systems.
Steering Wheel for Mice
A specialized add-on module for our Virtual Reality systems, designed to enable precise investigation of visual decision-making in head-fixed mice through intuitive left or right turn choices.
JetBall- Spherical Treadmill
The JetBall is a VR system combining an air-cushioned spherical treadmill and a high-res TFT monitor ring or a dome, with optional operant devices allowing mice and rats to navigate virtual environments while researchers track brain activity.
Vision Assessment in Mice & Rats
Measuring Visual Clarity and Contrast Sensitivity with Accuracy
qOMR – Visual Acuity and Contrast Sensitivity
The optomotor response (OMR) is a reflex used to assess visual function. To evoke OMR, a mouse watches a striped pattern rotating within a cylinder. Stimulus-correlated head movements are quantified to determine visual thresholds.
The PhenoSys qOMR (quantitative OMR) is a unique system that automatically measures the OMR with minimal experimenter effort. It uses a virtual stimulation cylinder that continuously aligns with the animal´s head position. Based on real-time head tracking, quantitative OMR measurements run fully automatically and objectively. This is a PhenoSys Collaboration product that is brought to market together with its developer, Dr. Friedrich Kretschmer.
- Simple, robust, and non-invasive test to examine vision in rodents
- Fully automated measurement and analysis: no manual positioning of the stimulus, no specially trained experimenter required, time and cost effective, and unbiased
- As a reflex, OMR measurements do not require animal training
- Freely behaving animals, no surgery, no fixation
- Flexible, user-friendly experimental design and data handling.
qOMR-XT – Vision testing for rats
The optomotor response measurement (OMR) is a proven method to assess visual function in rodents. The PhenoSys qOMR-XT extends the qOMR product line to applications where larger animals, such as adult rats are to be studied. It is a unique system that objectively measures the OMR with minimal experimenter effort. Based on real-time head tracking, quantitative OMR measurements automatically provide visual acuity and contrast sensitivity. This is a PhenoSys Collaboration product brought to market together with its developer, Dr. Friedrich Kretschmer.
Monitoring & Tracking Solutions for Advanced Behavioral Studies
Phenosys provide researchers with sophisticated, integrated systems designed to revolutionize the study of individual animals in housed in groups. We understand the complexities of behavioral research and the critical need for accurate, continuous, and undisturbed data collection.
At the core of our robust Housing and Monitoring Solutions is advanced Radio-Frequency Identification (RFID) technology. This proven technology allows for precise, individual animal identification and tracking, forming the backbone of our automated systems and enabling the continuous, data collection that defines our solutions.
- Reduced operator interaction
- Animal friendly group housing
- Continuous 24/7 operation and data collection
- Precise activity measurement for individuals
IDspyder
Scalable system for adding animal tracking to test arenas.
IDsorter
For individual access from group housing to testing arenas.
MultiMouseMonitor
Smart surveillance of group housed animals.
ColonyRack
System for the automated tracking of a large group of mice.
IDrevolyzer
Combines multiple running wheels with group housing.
Metabolic Measurement: Indirect Calorimetry
Advanced push-button system for automated measurement of metabolic rate, energy expenditure, respiratory exchange and more in mice, rats, and birds.
Key Features
- Automated Metabolic Analysis
Automated measurement and calculation of key metabolic parameters (metabolic rate, energy expenditure, respiratory exchange ratio) - Comprehensive Data
Precise analysis of O2 consumption, CO2 production, and water vapor evaporation. - Precise Mesaurement
Reliable data for understanding animal metabolism, nutrition, thermoregulation, activity, and energy balance. - One Size Fits Many
Solutions for small animals including mice, rats, and birds.
Mini2P Turnkey System - High-Resolution Imaging in Freely Moving Animals
The Mini2P is a miniature two-photon microscope for fast, high-resolution, multi-plane calcium imaging in freely moving mice. Weighing under 3 g with a highly flexible connection cable, Mini2P enables stable imaging without hindering animal behaviour. Its optimized optical system allows stable simultaneous recordings of neuronal activity of more than thousand cells in different brain regions.
PhenoSys presents this innovative technology as a turnkey solution, including the miniature 2P microscope with its fiber optics, laser, detection unit and flexible DAQ hardware and software. Get your complete system and have it ready to run within hours.