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Electrophysiology

Perfusion

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ALA Scientific Instruments has been helping researchers equip their labs for challenging experiments in biophysics and cellular electrophysiology.

Website: https://alascience.com

Gravity Flow Perfusion

Gravity Flow Perfusion

Valve Controlled Gravity Perfusion Systems – 4 channel
Valve Controlled Gravity Perfusion Systems – 4 channel

The VC3-4xG Series from ALA includes 4 channel valve controlled gravity perfusion systems that fulfill the basic requirements of the student lab but can also be optimized to fit the most demanding applications of patch clamp recording and/or imaging. All VC3-4xG Series systems provide electronic control of solution exchange which improves reproducibility over manual methods. These systems are designed to minimize electronic noise so sensitive electro physiological recordings are not disturbed.

Features
  • Choice of low-maintenance pinch valves or fast-response solenoid valves
  • Customizable reservoir sizes and materials
  • DAQ control via analog or TTL input
  • Valve control through DAQ, Valve Commander software, or controller
  • Spill sensor with automatic shutoff to protect microscope optics
  • Valve open and close timestamps via analog or digital output

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Valve Controlled Gravity Perfusion Systems – 8 channel
Valve Controlled Gravity Perfusion Systems – 8 channel

The VC3-8xG Series from ALA includes 8 channel valve controlled gravity perfusion systems that fulfill the basic require ments of the student lab but can also be optimized to fit the most demanding applications of patch clamp recording and/or imaging. All VC3-8xG Series systems provide electronic control of solution exchange which improves reproducibility over manual methods. These systems are designed to minimize electronic noise so sensitive electrophysiological recordings are not disturbed.

Features
  • Choice of low-maintenance pinch valves or fast-response solenoid valves
  • Customizable reservoir sizes and materials
  • DAQ control via analog or TTL input
  • Valve control through DAQ, Valve Commander software, or controller
  • Spill sensor with automatic shutoff to protect microscope optics
  • Valve open and close timestamps via analog or digital output

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Simple Perfusion Kit – 4 channel
Simple Perfusion Kit – 4 channel

The SPK-4 from ALA is a low-cost 4 channel simple perfusion kit. Typical applications include intracellular and extracellular recording, patch clamping, and imaging applications. The SPK-4 is especially useful for all types of bath perfusion applications and for student labs.

Features
  • Ease of assembly
  • Manual valve flow control
  • DAQ control via analog or TTL input
  • Replaceable parts

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Simple Perfusion Kit – 8 channel
Simple Perfusion Kit – 4 channel

The SPK-8 from ALA is a low-cost 8 channel simple perfusion kit. Typical applications include intracellular and extracellular recording, patch clamping, and imaging applications. The SPK-8 is especially useful for all types of bath perfusion applications and for student labs.

Features
  • Ease of assembly
  • Manual valve flow control
  • DAQ control via analog or TTL input
  • Replaceable parts

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µFlow: Micro-Volume Perfusion System

µFlow: Micro-Volume Perfusion System

µFlow: Micro-Volume Perfusion System

The μFlow™ from ALA is a micro-volume perfusion system that addresses the growing need to preserve precious compounds during electrophysiology and imaging experiments. ALA has accomplished this through adaptation of our unique Micromanifold® technology for the perfusion of very low solution volumes to cells and tissues.

Features
  • Extremely low dead volume from reservoir to tip (<6.4μL)
  • Prevention of backflow and cross contamination via micro check valves
  • Manual control through VC3 controller or computer control through software
  • Pneumatic control valves for reduction of dead volume
  • 4- or 8- channel option
    The μFlow™ drastically reduces dead volume that is normally associated with pressurized perfusion systems. All tubing that solution normally flows through is minimized. Pressure is applied to a closed vessel which sends solution through a special Quartz MicroManifold® .

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Pressurized Flow Perfusion

Pressurized Flow Perfusion

VC3-8xP : Pressurized 8 Channel
VC3-8xP Perfusion System : Pressurized 8 Channel

The VC3-8xP Series from ALA includes 8 channel valve controlled pressurized perfusion systems that fulfill the basic requirements of the student lab but can also be optimized to fit the most demanding applications of patch clamp recording and/or imaging. All VC3-8xP Series systems provide electronic control of solution exchange which improves reproducibility over manual methods. These systems are designed to minimize electronic noise so sensitive electrophysiological recordings are not disturbed.

Features
  • Choice of low-maintenance pinch valves or fast-response solenoid valves
  • Customizable reservoir sizes and materials
  • DAQ control via analog or TTL input
  • Valve control through DAQ, Valve Commander software, or controller
  • Spill sensor with automatic shutoff to protect microscope optics
  • MilliManifold TM and Quartz MicroManifold® perfusion outlet options for low volume and rapid solution exchange applications
  • Valve open and close timestamps via analog or digital output

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VC3-4xP : Pressurized 4 Channel
VC3-4xP Perfusion System : Pressurized 4 Channel

The VC3-4xP Series from ALA includes 4 channel valve controlled pressurized perfusion systems that fulfill the basic requirements of the student lab but can also be optimized to fit the most demanding applications of patch clamp recording and/or imaging. All VC3-4xP Series systems provide electronic control of solution exchange which improves reproducibility over manual methods. These systems are designed to minimize electronic noise so sensitive electrophysiological recordings are not disturbed.

Features
  • Choice of low-maintenance pinch valves or fast-response solenoid valves
  • Customizable reservoir sizes and materials
  • DAQ control via analog or TTL input
  • Valve control through DAQ, Valve Commander software, or controller
  • Spill sensor with automatic shutoff to protect microscope optics
  • Valve open and close timestamps via analog or digital output

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OctaFlow II: Multi-function Perfusion System
OctaFlow II: Multi-function Perfusion System

The OctaFlow II ™ from ALA is our most advanced drug application device for electrophysiology and imaging research. This fast perfusion system is designed to meet the needs of basic science and drug discovery researchers. Software control of all perfusion parameters makes the OctaFlow II ™ superior to all other perfusion systems.

Features
  • Choice of low-maintenance pinch valves or fast-response solenoid valves
  • Valve-control of solution flow instead of motorized manipulation of barreled pipettes, minimizing sample losses following solution exchange
  • Keyboard solution selection, for exchange “on the fly”
  • Trigger in /out for synchronization with data acquisition systems
  • Preprogrammed solution delivery through software
  • Rapid flush mode for easy cleaning
  • Programmable pressurization of fluids for optimal solution flow
  • Programmable analog outputs for valve identification, step number, or pressure information to data acquisition

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MapplingLab based in Oxford UK, manufactures data acquisition and scientific equipment for cardiac electrophysiological research.

Website: https://mappinglab.com

MappingLab Heart / Tissue Perfusion Systems

Heart / Tissue Perfusion Systems

MVC-801 Controller
MappingLab Heart / Tissue Perfusion Systems

8 pinch-valve perfusion system is designed for delivering experimental solutions in a controlled manner.

Features
  • 8 independent valves.
  • Versatile operation & free choice of any combination.
  • Flexible manual or computer control.
  • Programmable complex sequence.
  • High-precision solution delivery.
Compatibility
  • DrugDelivery
  • Windows 7, 8, 10

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Heart/Tissue Perfusion Chamber
MappingLab Heart / Tissue Perfusion Systems

The small perfusion chamber is constructed for ex vivo experiments performing on isolated small hearts and organs from rodents as well as tissues in the controlled temperature conditions. It is designed for utilizing optical mapping recording, tissue dissection and stimulation that requires fast changes of solution.

Features
  • Dimension: 15 x 15 x 6 cm,working chamber: 6 x 6 x 2 cm.
  • Chamber sizes can be customized.
  • Silicon chamber base.
  • 6 holes at the sides for fixing the cannula, solution tubes and stimulation electrode, etc. using mini ball joint clamps.
  • Controlled temperature by a water bath or a temperature controlling system.
  • Applicable to the solution bubbled with gas

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