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August 9, 2021
category: General
MagRes – MRI Compatible Headstage for small animal research

The MagRes from Blackrock Microsystems is a single-unit, analogue recording, MRI-compatible headstage available for small animal and non-human primate researchers to directly correlate neural activity with haemodynamic changes detected on MRI for awake and responsive subjects.

The MagRes has been successfully tested for heating, migration and image artifact in the MRI environment up to 16.4Tesla and can record single unit spikes and wide band signals while in an MRI during scan without distorting image (no imaging artifact).

Lightweight and small (16 ch = 0.5gm,8mm x 19mm x 2mm, 32 ch <1.0gm, 16mm x 19mm x 2mm), the MagRes has a small form factor allowing the animal to comfortably wear the analogue headstage while in the MRI during operation.

The MagRes provides an isolated low-impedance output that guarantees signal integrity, minimises noise pickup by cables and ensures maximum common-mode noise rejection when using the Cereplex A. The MagRes headstage is compatible with MicroFlex Array, Cereplex Direct, CereStim and the Cerebus which are all available from Blackrock Microsystems.

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August 9, 2021
category: General
IR VIVO™ – NIR-II Preclinical Multispectral Imager

The IR VIVO™ by Photon etc is an NIR-II in-vivo multispectral, preclinical imager for small animal studies. It provides non-invasive spectral imaging in the first (NIR) and second (NIR-II) biological windows, from 900-1620nm. The IR-VIVO™ provides multispectral or hyperspectral infrared imaging for in-vivo research on small animals or other living organisms.

Visualize microvasculature, monitor blood flow and metabolic imaging, monitor heart and respiratory rates (contact free), monitor cell environment (pH, lipid, mRNA) and identify cancer tissue and guide real time surgery. The IR-VIVO™ is ideal for in-vivo applications involving detection in the second biological window, in particular drugs, toxicology, diagnostic, IR tracers and labels and development studies. In addition, the IR-VIVO™ can be used for the evaluation of oxygenated versus deoxygenated blood ratios and nanoparticles distributions.

A combination of fast acquisition speed, multicolour imaging, high spatial resolution and good penetration depth (10x greater than traditional visible optical systems) means the IR-VIVO™ captures both structure and function in its spectral images. Emission of several fluorophores can be isolated with a high-efficiency tunable filter and ultra-low noise scientific-grade InGaAs camera (Alizé 1.7 or ZephIR 1.7).

IR-VIVO™ performs multispectral imaging using a filter wheel and hyperspectral imaging with a continuously tunable spectral range from 500 to 1620nm and a spectral resolution of <4nm. By virtue of its Hypercube VBG global high-efficiency filters and high-speed scientific grade SWIR cameras, IR VIVO™ can accurately isolate the emission of several IR labels. The imager provides the perfect tool for all applications that involve detection in the second biological window.

The IR VIVO™ is non-ionizing & non-invasive and measures 77 x 60 x 98cm tabletop size.

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August 9, 2021
category: General
BrainDancer™ fMRI Calibration System for Brain Imaging

BrainDancer™ by ALA Scientific is a commercial-grade dynamic phantom, designed to identify and correct systematic scanner-induced noise using ALA Scientific’s deep learning algorithm, NoiseNet™. BrainDancer™ can be used in a variety of applications such as Macropatch, Single Channel and whole cell recording, Cardiac Rhythmicity, Systems Neuroscience, Exocytosis, Brain/Spinal cord slice recording and Retinol Physiology.

Features include:

  • Pneumatically controlled movement
  • Pneumatically controlled movement
  • Rotating inner cylinder to produce T2* changes within voxels
  • Imitates BOLD amplitudes of human brains
  • Motion is synchronized with MR scanner
  • Externally triggered programmable sequences
  • NoiseNet™ software for temporal noise estimation
  • Cleaner signal and stronger results

The BrainDancer™ dynamic phantom not only improves the signal-to-noise ratio, but can also be used for standardisation of protocols and normalisation between scanners.

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August 9, 2021
category: General
Kinetix22 High Speed BI sCMOS Camera

The new 5.7MP back-illuminated Kinetix22 scientific CMOS (sCMOS) camera from Teledyne Photometrics delivers high speed, high dynamic range, and low noise imaging with an optimized field of view for microscopes and other optical devices with industry standard C-mount image ports. It is the camera of choice or researchers using super-resolution imaging, light sheet microscopy, multi-channel and voltage imaging.

The Kinetix22 features four modes, allowing users to prioritize different camera specs, optimise imaging, and avoid compromise. The 8 bit Speed mode offers 498 fps across the full frame, 12 bit Sensitivity mode offers low 1.2 e- read noise while operating at ~90 fps, 12 bit Ultra Low Noise mode offers sub electron read noises of 0.7 e- for EMCCD-like sensitivity, and 16 bit Sub Electron mode has a large full well capacity for imaging varied signal levels in a sample.

The Kinetix22 delivers a tremendous 498 frames per second (fps), full frame across the entire 22 mm diagonal field of view. This speed significantly outperforms typical sCMOS devices while featuring a higher megapixel sensor.

The optimized line time results in a data rate of almost 3000 megapixels/second, around 7x greater than typical sCMOS devices and achieves a near-perfect 95% quantum efficiency.

The Kinetix22 featuresS6.5 µm x 6.5 µm pixels, the accepted standard for most live cell applications using 40x and 60x magnification. This pixel size provides highly detailed images across the imaging plane and is most suitable for the broadest range of microscope objectives.

Also featuring Pattern Noise Reduction Technology and Correlated Noise Reduction Technology, the Kinetix22 delivers clean, pattern-free images with minimal pixel defects, delivering improved image quality in low light conditions. By bringing the light in from the back of the sensor, photons land directly onto the light receiving surface, maximizing light collecting capability. This allows for the weakest signals to be displayed as high quality images, even if the sample typically only emits a handful of photons.

PCIe and USB 3.2 interfaces are supported and the spectrum capabilities are UV (200-400nm), Visible (400-700nm) and Near Infrared (700-1000nm).

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June 23, 2021
category: General
Photometrics Kinetix Ultra Fast, 10.2MP, 500 FPS sCMOS Camera

The back-illuminated Kinetix Scientific CMOS (sCMOS) camera from Teledyne Photometrics delivers the fastest speed and the largest field of view with the most balanced pixel size and near perfect 95% quantum efficiency. This makes it the camera of choice in fluorescence microscopy, high content imaging, biochip, microarray and genomic applications. When imaging at high-speed, sensitivity becomes key. This is why Teledyne Photometrics developed a new, sub-electron mode with 0.7e- read noise, making the Kinetix sCMOS camera the most versatile low-light imaging camera ever made.

Taking advantage of an 8-bit readout mode, the Kinetix sCMOS camera delivers a tremendous 500 frames per second (fps), full frame with a 29.4 mm diagonal field of view. The optimized line time allows the speed to significantly outperform typical sCMOS devices, delivering over 5000 megapixels/second – over a 10-fold improvement.

The 29.4 mm square sensor of the Kinetix camera is designed to increase throughput, maximize the amount of data captured in a single frame and take full advantage of new, larger field of view microscopes. At 29.4 mm diagonal, the 10.2MP Kinetix sensor has a 2.4x larger imaging area than typical sCMOS cameras allowing the user to significantly speed up data acquisition.

The camera achieves a near-perfect 95% quantum efficiency.By bringing the light in from the back of the sensor, photons land directly onto the light receiving surface, maximizing light collecting capability. By combining this 95% quantum efficiency with a sub-electron low 0.7 e- read noise it delivers the most sensitive sCMOS camera available.

The Kinetix camera features 6.5 µm x 6.5 µm pixels, the accepted standard for most live cell applications using 40x and 60x magnification. This pixel size provides highly detailed images across the imaging plane and is most suitable for the broadest range of microscope objectives. It also features Pattern Noise Reduction Technology and Correlated Noise Reduction Technology to ensure that it delivers clean, pattern-free images with minimal pixel defects, delivering improved image quality in low light conditions.

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June 16, 2021
category: General
Mightex Polygon UHC – Ultra High Contrast DMD Pattern Illuminator

Mightex’s market-leading Polygon DMD pattern illuminators provide precise spatiotemporal control of light with subcellular resolution, making them the perfect illumination tool for life science research. The Polygon UHC incorporates the latest in digital micro-mirror technology to achieve the greatest available contrast ratio of 10,000,000:1, unlocking countless research opportunities for the bioscience community.

The Polygon UHC can create opto-genetic grid scans with a greater number of grids for higher spatial resolution circuit mapping. This allows the user to target optical stimulation more precisely to smaller regions of interest.

With the Polygon UHC, only the regions of interest are targeted by photo-stimulation, decreasing unwanted photo-activation of surrounding light sensitive areas in the tissue of interest.

The Polygon UHC produces more grey levels, leading to seamless optical intensity application. Further, this larger dynamic range is relevant for studies requiring fine control of low intensity stimulation parameters, such as retina-related studies.

The Polygon UHC can be seamlessly integrated with 2-photon microscopes allowing for easy transition between patterned stimulation and 2-photon imaging.

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May 28, 2021
category: General
Teledyne SP Devices: ADQ14 – multi-channel, 14-bit digitizers

The Teledyne SP Devices ADQ14 is a high-performance 14-bit data acquisition platform which offers complete and versatile solutions for advanced measurements. It comes with a generous set of hardware, firmware, and software features which help simplify integration. Every aspect of the measurement process from the detector, real-time signal processing, data visualization, and more are included. Applications include LiDAR, RADAR, wireless communication, high-speed data recording, test and measurement, ultrasonic ranging, time-of-flight scientific instruments, swept-source OCT, Thomson scattering and more.

The Teledyne SP Devices 14-bit digitizer family, ADQ14 with 1, 2, or 4 channels and 0.5, 1, or 2 GSPS sampling rate per channel comes in six different form factors and is available with either AC or DC coupling (ADQ14AC and ADQ14DC) and variable DC-bias. Form factors include USB 3.0, 10 GbE, PCIe (dual-slot) and SSPCIe (single-slot PCIe), PXIe and MTCA.4. This simplifies retrofitting in existing systems as a drop-in replacement.

Selected features include flexible choice of sampling rate, channel count, and multi-board synchronization, advanced programmable analogue front-end supporting high input bandwidth, open FPGA for real-time DSP and stand-alone application-specific firmware, up to 6 GByte/s data transfer rate and optional peer-to-peer streaming to GPU and wide selection of form factors to help simplify integration. The software development kit is available both for Windows and Linux with a number of host interface options.

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April 26, 2021
category: General
pco.panda 26 DS – Double Shutter PIV camera

The pco.panda 26 DS sCMOS camera from PCO offers outstanding double shutter capabilities, high resolution of 5120 x 5120 pixels, 26MPixel images with an inter-framing gap as low as 1 μs making it the camera of choice for effective double imaging – a prerequisite to perform all types of Particle Image Velocimetry (PIV) measurements. These include non-intrusive laser optical measurement techniques for research, diagnostics into flow analysis, turbulence, aerodynamics, microfluidics, chemical processing plants, spray atomization, spray dryers, rotary kilns, and combustion processes such as gas turbine combustors used for aero and marine applications.

Exposure times range from 6 μs to 350 ms and the frame rate is 7.1 fps @ 26MPixel. The dynamic range is 66dB, parasitic light sensitivity 1:10,000 so you can achieve a remarkably low readout noise and dark current.

In PIV, light scattering particles are added to the flow under test. A laser beam is formed into a light sheet, illuminating the scattering particles twice with a short pulse at a time interval Δt. The lower limit for this time interval is defined by the double image inter-framing time of the camera. The scattered light is recorded onto two consecutive frames of a high resolution digital camera. The shorter the double image inter-framing time, the higher the flow speeds which can be analysed.

The ultra compact housing design of the camera and interface provide easy integration. No external power supply is required and power and fast data transfer are through one single USB 3.1 cable. The camera comes with a 2 year warranty.

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April 26, 2021
category: General
i-SPEED7 High Speed Camera Series

IX Camera’s new i-SPEED 7 high speed camera series feature the newest Advanced Sensor Technology (AST) 3.2MP CMOS sensor to boast an unparalleled combination of features for the most demanding applications. Available in either colour or mono, the i-SPEED 717, 721, and 727 camera models are the most advanced, highest performing cameras in the iX cameras line of products. These models are packed with a long list of advanced features and include market-leading performance of 2.45 million fps and high-resolution. These features make the new i-SPEED 7 Series ideal for PIV, DIC, fluid dynamics, ballistics and a wide range of scientific research.

IX Cameras have added an optional electromechanical shutter to the new i-SPEED 7 Series. This new feature enables remote reference, automated calibration, and sensor protection during lens changes. The electromechanical shutter makes the new i-SPEED 7 Series ideal for field work where the camera is at a distance from the user and for DIC and PIV applications where the camera must not be moved after a calibration frame.

The i-SPEED 7 Series (717, 721, and 727) provides an increased 2072 x 1536 resolution @ 8,512 fps that raises throughput speeds to 27.1 GPixels/second (27.1 billion pixels processed every second) – at even higher frame speeds. The balance between resolution and frame rate produces amazingly clear images at impressive resolutions that are critical for accurate motion analysis.The i-SPEED 7 features Trigger, Sync In/Out, and Exposure Out on the rear panel. Exposure Out can be switched to Synchronized Lighting Control.

iX Cameras engineers combined the i-SPEED 7 Series instrumentation and rugged models into one innovative camera housing – ideal for both laboratory and challenging field environments. The sturdy, rugged design features a high-G rated two-piece aluminum enclosure for exceptional protection which also includes a user removable handle to provide greater flexibility when mounting the camera to a static frame. Removing the handle exposes fixing points to facilitate the connection of other components such as the CDUe or lights, displays, booms, etc.

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Recording at high speeds with high resolutions produces a great deal of data. The i-SPEED 7 Series cameras can be configured with up to 2TB of internal SSD storage. They can be designed to allow for easy upgrades between models as performance or application requirements increase. You can also add additional memory and options such as xSSD or upgrade to a higher performance model.

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April 7, 2021
category: General
Pixelink PL-X 10GigE Industrial Cameras

Pixelink’s new high performing PL-X machine vision camera series with 10 GigE interface give you speed, accuracy and reliability in a quick and easy set-up. Four camera models are available and include 7MP, 12MP, 20MP and 24MP versions and incorporate Sony’s Pregius Sensor line including the newest 4th generation sensors.

Additional features including Power-over-Ethernet (PoE), Trigger-over-Ethernet (ToE), IEEE 1588 clock synchronization (PTP) and high speed data transfer making the cameras suitable for applications such as automated inspection, sports analysis, VR and AR applications, broadcasting, 3D mapping, research and multi-camera application requiring synchronization.

Sensor features such as back-illumination and global shutter support the capture of accurate, reliable, distortion-free images of large moving objects and include high bandwidth for high-speed imaging. Enclosed or board level versions available.

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